Mutagenicity testing of 3 hallucinogens: LSD, psilocybin and‡ 9-THC using the micronucleus test
Cellular and Molecular Life Sciences March 1, 1978 Greg Went 43 citations
No significant increase in micronuclei—a marker of genetic damage—was observed in mice given three logarithmically increasing doses of LSD, psilocybin, or delta-9-THC. Azathioprine (Imuran), used as a positive control, caused a statistically significant increase in micronucleated cells. These results suggest that, under the conditions tested, these compounds did not induce detectable mutagenic activity in the micronucleus assay.