LSD and Chromosomes
JAMA November 3, 1969 Joe‐hin Tjio 55 citations
In a double-blind study, chromosomes from lymphocytes of 32 patients were examined before and after they took pure LSD in a controlled therapeutic setting, along with five black-market users who received pure LSD in a research setting. Statistical analysis showed no significant difference in chromosomal aberration rates before and after LSD. A follow-up study of eight normal subjects who had taken LSD in earlier experiments, using the same cytogenetic methods, also found no evidence of chromosomal damage. The results consistently indicate that, based on 72-hour cultures, there is no definite evidence that pure LSD damages human lymphocyte chromosomes in vivo.