Untoward Reactions to Lysergic Acid Diethylamide (LSD) Resulting in Hospitalization
New England Journal of Medicine December 2, 1965 William A. Frosch, Edwin Robbins, Marvin Stern 115 citations
A sudden increase in psychiatric admissions at Bellevue Hospital following LSD ingestion prompted a review of the history of the drug. Medical research typically progresses from clinical observation to laboratory experiment, but drugs like LSD, first synthesized in the lab, can create new clinical syndromes or etiologies of old syndromes as by-products of abuse or physician error. The text describes this pattern of discovery and the clinical consequences of LSD use.