Stability Study of LSD Under Various Storage Conditions
Journal of Analytical Toxicology October 1, 1998 Zhi Li, A. J. Mcnally, Honggang Wang et al. 50 citations
LSD in pooled urine is stable for up to 4 weeks at 25 degrees C in the dark, with no significant loss. At 37 degrees C, a 30% loss occurred after 4 weeks, and up to 40% at 45 degrees C. Amber glass or nontransparent polyethylene containers preserved LSD concentration under any light conditions; stability in transparent containers depended on distance from light source, wavelength, exposure time, and intensity. Prolonged heat in alkaline pH converted 10 to 15% of LSD to iso-LSD; under acidic conditions, less than 5% converted. Trace metal ions catalyzed decomposition, preventable by adding EDTA. Proper storage is essential for accurate analytical testing.