Confirmation of LSD Intoxication by Analysis of Serum and Urine
Journal of Analytical Toxicology May 1, 1990 Margaret M. Mccarron, Clifford B. Walberg, Randall C. Baselt 40 citations
Among 31 patients with suspected LSD intoxication, a radioimmunoassay (RIA) with a detection limit of 0.1 ng/mL identified LSD in 13 blood and urine specimens from 14 patients. High-performance liquid chromatography (HPLC) with a detection limit of 0.5 ng/mL confirmed LSD in 9 of 13 serum and 11 of 13 urine specimens that were RIA-positive. Of 18 patients ultimately diagnosed with LSD intoxication, RIA detected LSD in 14 and HPLC in 11. All 13 patients with other diagnoses had negative results by both methods. The authors conclude that a commercially available RIA provides reliable qualitative laboratory confirmation of LSD intoxication.