Detection of LSD and Metabolite in Rat Hair and Human Hair
Journal of Analytical Toxicology September 1, 1996 Yoshiro Nakahara, Ruri Kikura, Kazunori Takahashi et al. 36 citations
Lysergic acid diethylamide (LSD) and its metabolite norLSD can be detected in hair after administration. In pigmented rats given daily doses of 0.05 to 2 mg/kg for 10 days, LSD was found in newly grown hair even at the lowest dose, while norLSD appeared only at the highest dose. Analysis of hair from 17 self-reported LSD users detected LSD in two samples. The methods used gas chromatography-mass spectrometry and high-performance liquid chromatography with fluorometric detection, demonstrating the feasibility of hair analysis for LSD exposure.