Psilocybin as a discriminative stimulus: Lack of specificity in an animal behavior model for ?hallucinogens?
Psychopharmacology February 1, 1982 Jon Koerner, James B. Appel 19 citations
Rats can distinguish the tryptamine hallucinogen psilocybin from saline in a two-lever choice task. The psilocybin cue generalizes to psilocin and LSD, but not to mescaline, suggesting that the hallucinogenic effects of these drugs in humans may not align with their discriminative stimulus functions in animals, and that these compounds may not belong to a single drug class.