Geha Mental Health Center
2 papers in the library · 109 citations · publishing 2000-2001
European Psychiatry March 1, 2001 Z. Zemishlany, Dov Aizenberg, Abraham Weizman 70 citations
MDMA (Ecstasy) moderately to profoundly increases sexual desire and satisfaction in more than 90% of users, and orgasm is delayed but perceived as more intense. However, erection is impaired in 40% of men, indicating that MDMA enhances subjective sexual experience while impairing sexual performance.
International Clinical Psychopharmacology January 1, 2000 A Lerner, Marc Gelkopf, Igor Oyffe et al. 39 citations
A small pilot open study tested whether clonidine, a drug that reduces sympathetic nervous activity, could help people with hallucinogen persisting perception disorder (HPPD) caused by LSD. Eight patients who had had HPPD for at least three months and had been drug-free for at least three months took a low dose of clonidine (0.025 mg three times daily) for two months. Two patients dropped out. Among the six who completed the study, scores on the Clinical Global Impression Scale dropped from an average of 5.25 (severe) to 2.5 (mild), and self-reported symptom severity fell from 4 to 2 on a 0-5 scale. The findings suggest that clonidine may alleviate LSD-related flashbacks linked to excessive sympathetic nervous activity in some patients.