LSD and chromosomes. A controlled experiment
JAMA November 3, 1969 J. H. Tjio 15 citations
Chromosomes from lymphocytes were examined in 32 patients before and after they took LSD as part of controlled research, and in five black-market users who received pure LSD in a research setting. Statistical analysis showed no significant difference in chromosomal aberration rates before and after LSD. A follow-up study of eight normal subjects who had taken LSD in earlier experiments also found no evidence of damage. The results consistently support the conclusion that, at this time, there is no definite evidence that pure LSD damages chromosomes of human lymphocytes in vivo as studied from 72-hour cultures.