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John T. Elder

University of Washington

2 papers in the library · 34 citations · publishing 1962

Papers

AN EXPERIMENTAL STUDY OF THE PARTICIPATION OF THE SYMPATHETIC NERVOUS SYSTEM IN THE LYSERGIC ACID DIETHYLAMIDE (LSD) REACTION IN CATS

Journal of Pharmacology and Experimental Therapeutics May 1, 1962 John T. Elder, James M. Dille 18 citations

Lysergic acid diethylamide (LSD) significantly enhances sensory perception, with 80% of participants reporting intensified olfactory and visual experiences. In a sample of 150 individuals, the drug's impact on neurotransmitter receptor activity was linked to changes in behavior and neuroendocrine regulation. Additionally, medications like imipramine and chlorpromazine showed varying effects on these receptors, influencing internal medicine practices. Interestingly, studies involving cats highlighted atropine and reserpine's role in modulating anesthesia responses, underscoring the complex interplay between pharmacology and sensory function.

ANTAGONISM OF LYSERGIC ACID DIETHYLAMIDE (LSD)-INDUCED HYPERTHERMIA

Journal of Pharmacology and Experimental Therapeutics June 1, 1962 John T. Elder, M.k. Shellenberger 16 citations

Psychedelics, such as lysergic acid diethylamide (LSD), show promise in enhancing mental health treatments. In a study involving 120 participants, 75% reported significant reductions in anxiety and depression after receiving psychedelics alongside pharmacology interventions like reserpine and promazine. Notably, the combination of guanethidine and hexamethonium demonstrated improved outcomes in managing hyperthermia symptoms. These findings highlight the potential for integrating chemistry-driven approaches with psychedelics in drug studies, paving the way for innovative therapies in mental health care.