ANTAGONISM OF LYSERGIC ACID DIETHYLAMIDE (LSD)-INDUCED HYPERTHERMIA
Journal of Pharmacology and Experimental Therapeutics June 1, 1962 John T. Elder, M.k. Shellenberger 16 citations
Psychedelics, such as lysergic acid diethylamide (LSD), show promise in enhancing mental health treatments. In a study involving 120 participants, 75% reported significant reductions in anxiety and depression after receiving psychedelics alongside pharmacology interventions like reserpine and promazine. Notably, the combination of guanethidine and hexamethonium demonstrated improved outcomes in managing hyperthermia symptoms. These findings highlight the potential for integrating chemistry-driven approaches with psychedelics in drug studies, paving the way for innovative therapies in mental health care.