Serotonin Release from Brain Slices by Electrical Stimulation: Regional Differences and Effect of LSD
Science September 22, 1967 Thomas N. Chase, George R. Breese, Irwin J. Kopin 1 citation
Slices of rat brain that had taken up radioactive serotonin, either in a living animal or in a laboratory dish, were washed and then electrically stimulated. This caused a substantial release of the added serotonin, and to a smaller degree its breakdown products. The amount released depended on which brain region was tested, and the release was blocked by lysergic acid diethylamide (LSD).