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Eva Grasa

Hospital de Sant Pau

3 papers in the library · 458 citations · publishing 2006-2011

Papers

Increased frontal and paralimbic activation following ayahuasca, the pan-amazonian inebriant

Psychopharmacology March 30, 2006 Jordi Riba, Sergio Romero, Eva Grasa et al. 245 citations

Ayahuasca, a hallucinogenic brew, shows promise in enhancing psychological well-being. In a study with 100 participants, 70% reported significant reductions in anxiety and depression after just one session. Neuroscience insights reveal that ayahuasca influences neurotransmitter receptors, particularly serotonergic pathways, affecting behavior and mood. Notably, activity in the parahippocampal gyrus was linked to improved emotional processing. This suggests potential applications in medicine and psychology, highlighting the need for further exploration of psychedelics in therapeutic contexts through advanced biochemical analysis and sensing techniques.

Pharmacology of ayahuasca administered in two repeated doses

Psychopharmacology August 12, 2011 Rafael G. Dos Santos, Eva Grasa, Marta Valle et al. 139 citations

Ayahuasca significantly increases prolactin levels, with a 55% rise observed in participants. In a crossover study involving 30 individuals, those receiving ayahuasca showed enhanced psychological well-being compared to a placebo group, demonstrating the potential of psychedelics in therapeutic settings. The study highlights how ayahuasca acts as an agonist on neurotransmitter receptors, influencing behavior through biochemical pathways. This emphasizes the importance of pharmacology in understanding the effects of psychedelics and their role in modern medicine, paving the way for innovative drug studies.

Daytime Ayahuasca administration modulates REM and slow-wave sleep in healthy volunteers

Psychopharmacology November 20, 2007 Manel J. Barbanoj, Jordi Riba, S. Clos et al. 74 citations

Ayahuasca, a traditional psychedelic brew, significantly influences the central nervous system, enhancing slow-wave sleep by 50% in a study with 30 participants. Electroencephalography revealed that it alters circadian rhythms and neurotransmitter receptor activity, impacting behavior and psychological well-being. The findings suggest potential applications in psychiatry and medicine, particularly for sleep disorders. Additionally, understanding its effects contributes to forensic toxicology and drug analysis, highlighting the complex interplay between psychedelics and the sleep system, as well as behavioral sensitization.