The Complications of 'Ecstasy' (MDMA)
JAMA March 18, 1988 Jamyl Alrazi 91 citations
A nearly fatal toxic reaction to 3,4-methylenedioxymethamphetamine (MDMA) occurred after an estimated dose of 100 to 150 mg, with blood levels of 6500 and 7000 ng/mL measured one and two hours after hospital admission. Before MDMA became a Schedule 1 drug in July 1985, psychiatrists used similar doses (100 to 150 mg) as a psychotropic catalyst and sensory disinhibitor without reported toxic effects. This case was part of a controlled study of MDMA metabolism and disposition in a single subject, performed before the drug was scheduled.