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David G. Moore

University of East London

2 papers in the library · 126 citations · publishing 2012

Papers

Neurobehavioral outcomes of infants exposed to MDMA (Ecstasy) and other recreational drugs during pregnancy

Neurotoxicology and Teratology March 5, 2012 Lynn T. Singer, David G. Moore, Sarah Fulton et al. 77 citations

MDMA (Ecstasy) use during pregnancy is linked to poorer motor quality and lower milestone attainment in infants at 4 months, with a dose-response relationship: greater exposure corresponds to worse motor outcomes. This first prospective study of prenatal MDMA exposure in humans compared 28 women who used MDMA during pregnancy with 68 polydrug-using women who did not, controlling for confounding factors. MDMA-using mothers had fewer prior births and more health, work, and social problems. Exposed infants were more likely to be male. The findings suggest risk to the developing infant and indicate that continued follow-up is needed to determine whether early motor delays persist or resolve.

DOI: 10.1016/j.ntt.2012.02.001 Full text MDMA Ecstasy Pregnancy Medicine +5

One-Year Outcomes of Prenatal Exposure to MDMA and Other Recreational Drugs

PEDIATRICS August 21, 2012 Lynn T. Singer, David G. Moore, Meeyoung O. Min et al. 49 citations

Heavier prenatal exposure to MDMA (ecstasy) predicted poorer mental and motor development in 12-month-old infants, with motor delays appearing in a dose-dependent manner. Lighter-exposed infants were comparable to nonexposed infants. No effects were found on language, emotional regulation, or parenting stress. The study involved 96 women in the United Kingdom—28 who used MDMA during pregnancy and 68 who did not—and used standardized developmental assessments.

DOI: 10.1542/peds.2012-0666 MDMA Ecstasy Medicine Psychomotor learning +6