MDMA polydrug users show processspecific central executive impairments coupled with impaired social and emotional judgement processes
Journal of Psychopharmacology March 30, 2006 Jonathon L. Reay, Colin Hamilton, David O. Kennedy et al. 91 citations
People who use MDMA (ecstasy) show impairments in specific cognitive processes—set shifting, memory updating, and social and emotional judgment—compared to polydrug users who do not take MDMA. These deficits remained significant even after accounting for use of other drugs. The findings suggest that recreational ecstasy use may harm prefrontal cortex functions.