Acute psychomotor, memory and subjective effects of MDMA and THC co-administration over time in healthy volunteers
Journal of Psychopharmacology September 3, 2010 Gjh Dumont, J. G. Coen van Hasselt, M. de Kam et al. 38 citations
Combining MDMA and THC does not worsen cognitive impairment beyond that caused by THC alone, but it does increase the desired subjective drug effects and perceived drug strength, which may explain why many young people use them together. In a placebo-controlled crossover trial with 16 healthy volunteers aged 18–27, THC alone produced more robust cognitive impairment than MDMA alone, and co-administration did not exacerbate single-drug effects on cognitive function. However, the combination enhanced subjective experiences compared with MDMA alone.