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J. G. Coen van Hasselt

3 papers in the library · 58 citations · publishing 2010-2025

Papers

Acute psychomotor, memory and subjective effects of MDMA and THC co-administration over time in healthy volunteers

Journal of Psychopharmacology September 3, 2010 Gjh Dumont, J. G. Coen van Hasselt, M. de Kam et al. 38 citations

Combining MDMA and THC does not worsen cognitive impairment beyond that caused by THC alone, but it does increase the desired subjective drug effects and perceived drug strength, which may explain why many young people use them together. In a placebo-controlled crossover trial with 16 healthy volunteers aged 18–27, THC alone produced more robust cognitive impairment than MDMA alone, and co-administration did not exacerbate single-drug effects on cognitive function. However, the combination enhanced subjective experiences compared with MDMA alone.

DOI: 10.1177/0269881110376687 MDMA Ecstasy Cannabis Psychomotor learning +10

Clinical Pharmacokinetics of Psilocin After Psilocybin Administration: A Systematic Review and Post-Hoc Analysis

Clinical Pharmacokinetics January 1, 2025 Marije E. Otto, Katelijne V. van der Heijden, Jan W. Schoones et al. 20 citations

The pharmacokinetic parameters of psilocin are consistent across different studies. This finding may help guide the further clinical development of psilocybin-based therapies.

DOI: 10.1007/s40262-024-01454-4 Full text Psilocybin Pharmacology Pharmacokinetics Post hoc +1