Attenuation of the disruptive effects of (+/-)3,4-methylene dioxymethamphetamine (MDMA) on delayed matching-to-sample performance in the rat.
Behavioral Neuroscience January 1, 2006 David N. Harper, Maree Hunt, Susan Schenk 26 citations
Acute MDMA exposure disrupts memory performance in rats, possibly by increasing confusion between events from previous and current trials. In a delayed matching-to-sample task, lengthening the intertrial interval from 5 to 15 seconds reduced this disruption, suggesting that separating current-trial to-be-remembered events from previous-trial events can attenuate MDMA's memory-impairing effects.