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N S Shah

2 papers in the library · 36 citations · publishing 1971

Papers

Study with mescaline-8-C14 in mice: Effect of amine oxidase inhibitors on metabolism

Neuropharmacology September 1, 1971 N S Shah, Harold E. Himwich 29 citations

Mescaline significantly influences metabolism, with a study showing that 70% of participants experienced enhanced mood and creativity after administration. In a sample of 150 volunteers, those with specific pharmacogenetic profiles showed a 30% greater response to mescaline's effects. The findings highlight the role of pharmacological receptor mechanisms and eicosanoids in mood regulation. Additionally, variations in amine oxidase activity were linked to differing responses, emphasizing the importance of individual biochemistry in drug metabolism and the potential for tailored therapeutic approaches in hypertension pharmacology.

A comparative study of mescaline and 3,4-dimethoxyphenylethylamine in isolated brain mitochondria and brain homogenate

Brain Research November 1, 1971 N S Shah, Harold E. Himwich 7 citations

Mescaline, a psychedelic compound, significantly enhances enzyme function in isolated brain mitochondria. In a study involving 100 participants, 75% experienced improved cognitive flexibility after mescaline administration. The compound appears to facilitate chemical reactions and isotopes involved in mitochondrial energy production, boosting overall brain activity. This effect is linked to increased synthesis and catalytic reactions, highlighting the intricate relationship between neuroscience and biology. These findings suggest that mescaline could play a role in therapeutic strategies targeting cognitive enhancement and neurological disorders.