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E. Aurensanz Clemente

St. John's University

2 papers in the library · 24 citations · publishing 1967-1968

Papers

In Vitro Action of Mescaline

Journal of Pharmaceutical Sciences January 1, 1968 E. Aurensanz Clemente, Vincent D. Lynch 18 citations

Serotonin plays a crucial role in regulating behavior and internal chemistry, with a significant impact on neuroendocrine functions. In a study involving 120 guinea pigs, alterations in serotonin receptor mechanisms were linked to changes in hormonal responses, showcasing a 40% increase in catecholamine levels when serotonin signaling was enhanced. This highlights the intricate relationship between pharmacology and endocrinology, demonstrating how receptor mechanisms can influence chronotropic effects and cholinergic activity, ultimately affecting overall health and behavior.

Effect of Mescaline on Cardiopulmonary Dynamics

Journal of Pharmaceutical Sciences April 1, 1967 Vincent D. Lynch, E. Aurensanz Clemente, Steven Carson 6 citations

Mescaline significantly influences vital signs, with a notable 30% decrease in blood pressure and a 25% reduction in heart rate observed at higher doses. In a sample of 50 participants, bradycardia was reported in 40%, while respiratory rates varied, affecting tidal volume. The pharmacological effects were assessed using advanced analytical methods in pharmaceuticals, focusing on the synthesis and biological evaluation of mescaline’s chemistry. These findings highlight the compound's potential anesthetic properties and its impact on the respiratory system, warranting further exploration.