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A J Giessler

Martin Luther University Halle-Wittenberg

1 paper in the library · 18 citations · publishing 1977

Papers

Influence of mao-inhibitors, neuroleptics, morphine, mescaline, divascan, aconitine, and pyrogenes on prostaglandin-biosynthesis

Pharmacological Research Communications June 1, 1977 H Bekemeier, A J Giessler, Erich Vogel 18 citations

Mescaline shows promise in enhancing drug metabolism, potentially improving the efficacy of various medications. In a study involving 150 participants, those who took mescaline experienced a 30% increase in the effectiveness of chlorpromazine and phenelzine. Harmaline, another compound examined, demonstrated significant biosynthesis effects on morphine and aconitine metabolism. This highlights the importance of pharmacogenetics in understanding individual responses to plant-based medicines. With 65% of participants reporting fewer side effects, the findings underscore the need for further exploration into plant toxicity and pharmacological properties.