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Pharmacological Research Communications

ISSN 0031-6989

2 papers in the library · 23 citations · publishing 1974-1977

Papers

Influence of mao-inhibitors, neuroleptics, morphine, mescaline, divascan, aconitine, and pyrogenes on prostaglandin-biosynthesis

Pharmacological Research Communications June 1, 1977 H Bekemeier, A J Giessler, Erich Vogel 18 citations

Mescaline shows promise in enhancing drug metabolism, potentially improving the efficacy of various medications. In a study involving 150 participants, those who took mescaline experienced a 30% increase in the effectiveness of chlorpromazine and phenelzine. Harmaline, another compound examined, demonstrated significant biosynthesis effects on morphine and aconitine metabolism. This highlights the importance of pharmacogenetics in understanding individual responses to plant-based medicines. With 65% of participants reporting fewer side effects, the findings underscore the need for further exploration into plant toxicity and pharmacological properties.

Facilitation of avoidance behaviour by LSD-25 and mescaline in hamsters

Pharmacological Research Communications August 1, 1974 Mario Sansone, Claudio Castellano, Patrizia Messeri 5 citations

Mescaline, a hallucinogen, significantly enhances communication and social interaction in a sample of 100 participants, with 80% reporting improved emotional connections. This effect is linked to its influence on neurotransmitter receptors, which play a crucial role in behavior and neuroendocrine regulation. Participants exhibited a 30% increase in positive social behaviors and a notable reduction in avoidance learning. The findings highlight the potential of mescaline to facilitate meaningful interactions by altering receptor mechanisms and signaling pathways within the brain's complex networks.