Fatal Intoxication from 3,4-Methylenedioxyamphetamine
Journal of Forensic Sciences January 1, 1979 Alphonse Poklis, Mary Ann Mackell, Wk Drake 25 citations
MDA is a potent central nervous system stimulant with effects similar to both amphetamine and mescaline. It causes peripheral vasoconstriction, tachycardia, pupillary dilation, and at high doses can lead to convulsions, hyperthermia, and behavioral changes. The 3,4-methyleneoxy group gives it psychopharmacological properties like mescaline. At a threshold dose of 80 mg, it produces marked perceptual distortions starting about 60 minutes after oral ingestion and lasting up to 8 hours. Subjective effects include intensified feelings, self-insight, and a strong desire to communicate. High doses may cause hallucinations.