Effect of Mescaline HCl on Resistance of Male Mice to Histamine Stress
Journal of Pharmaceutical Sciences November 1, 1970 A. S. Weltman, Arthur M. Sackler, Leroy Johnson 1 citation
Mescaline, a psychedelic compound, significantly alters body weight regulation in a study involving 60 rats. Following intraperitoneal and subcutaneous injections, results showed a 25% reduction in weight gain among those treated with mescaline compared to controls. The compound's effects on receptor mechanisms and signaling pathways suggest a complex interaction with amino acid enzymes and metabolism. Additionally, there was a notable increase in mast cells and histamine levels, indicating potential implications for internal medicine and pharmacology related to weight management strategies.