Clinical Comparison of Ketamine-Dexmedetomidine With Ketamine-Propofol During Canine Orchiectomy: A Randomized Study.
Veterinary medicine and science May 1, 2025 Mumin Gokhan Senocak 1 citation
Two anesthetic protocols for dog castration were compared: ketamine with dexmedetomidine (KD) and ketamine with propofol (KP). Both combinations provided effective anesthesia with similar intubation times (about 3 minutes). The KP group showed higher heart rate and blood pressure over time, suggesting better cardiovascular stability, but required additional top-up doses sooner (average 31 minutes sooner) and had lower blood oxygen levels (95.3% vs 97.7%). The KD group maintained higher oxygen saturation and needed fewer top-ups. The results indicate that while KP may offer better heart function support, it requires careful monitoring of body temperature and oxygen levels during surgery.