Management of Chemotherapy-Induced Peripheral Neuropathy (CIPN) in Oncologic Patients—A New Promise? Preliminary Results
Cancers October 15, 2025 Ron Batash, Noam Asna, Syed Ahsan Ali et al. 2 citations
A topical combination of amitriptyline and ketamine at new concentrations appears to provide safe and effective relief from chemotherapy-induced peripheral neuropathy (CIPN). This first clinical evaluation suggests the formulation is a promising symptomatic treatment, though larger randomized controlled trials and further study of transdermal delivery systems are needed to confirm the results and improve outcomes.