Acute Adverse Reactions to Lsd in Clinical and Experimental use in the United Kingdom
The British Journal of Psychiatry February 1, 1971 Nick Malleson 110 citations
Adverse reactions to LSD, such as suicide and prolonged psychosis, are well documented but mostly in cases of self-administration. A 1960 survey by Cohen pooled the experience of 44 American investigators who had published on LSD or mescaline, covering 5,000 subjects across 25,000 sessions. Only two suicides were directly linked to LSD. Psychotic reactions lasting more than 48 hours occurred at a rate of 0.8 per 1,000 experimental subjects and 1.8 per 1,000 patients. One-third of the investigators did not respond to the questionnaire, limiting the survey's completeness.