Coma, Hyperthermia, and Bleeding Associated with Massive LSD Overdose a Report of Eight Cases
Clinical toxicology January 1, 1975 John Klock, Udo Boerner, Charles E. Becker 78 citations
Eight people who snorted large amounts of pure LSD powder were seen within 15 minutes. They vomited, collapsed, and showed signs of overactive sympathetic nervous system, high body temperature, coma, and stopped breathing. Several had mild generalized bleeding, and all had evidence of platelet dysfunction. LSD concentrations in blood ranged from 2.1 to 26 ng/ml and in stomach contents from 1000 to 7000 mcg/100 ml. With supportive care, all patients recovered. Massive LSD overdose in humans is life-threatening and produces striking and distinctive symptoms.