LSD produces place preference and flavor avoidance but does not produce flavor aversion in rats.
Behavioral Neuroscience January 1, 1996 Linda A. Parker 41 citations
Lysergic acid diethylamide (LSD) produces a conditioned place preference only at the highest dose tested (0.2 mg/kg), and this preference is prevented by a single preexposure to the conditioning chamber (latent inhibition). When paired with sucrose, LSD doses from 0.05 to 0.2 mg/kg produce taste avoidance, but no dose produces an aversion to the taste as measured by the taste reactivity test. These results indicate that LSD, like other rewarding drugs, causes taste avoidance through a mechanism different from that of emetic drugs.