The Separation of Lysergide (LSD) from Related Ergot Alkaloids and Its Identification in Forensic Science Casework Samples
Journal of Forensic Sciences July 1, 1987 M. Japp, R. Gill, M. David Osselton 12 citations
Capillary gas chromatography with nonpolar bonded phase columns effectively separates lysergide (LSD) from related ergot alkaloids and its isomer lysergic acid methylpropylamide (LAMPA), providing retention indices for several ergot alkaloids. The method proved applicable to analyzing illicit LSD preparations, demonstrated by extracts from microdot tablets, card, and paper squares. In contrast, the high performance liquid chromatography (HPLC) systems tested could not achieve baseline resolution between LSD and LAMPA.