Jiaman Lin

Institute of Forensic Science

2 papers in the library · 10 citations · publishing 2023

Papers

Natural or artificial: An example of topographic spatial distribution analysis of mescaline in cactus plants by matrix-assisted laser desorption/ionization mass spectrometry imaging

Frontiers in Plant Science February 10, 2023 Jiaman Lin, Shuo Yang, Jiaojiao Ji et al. 8 citations

Mescaline, the hallucinogenic compound found in certain cacti such as Trichocereus pachanoi and Lophophora williamsii, is not distributed uniformly in natural plants. Using liquid chromatography-mass spectrometry and matrix-assisted laser desorption/ionization mass spectrometry imaging, the spatial distribution of mescaline was mapped at macroscopic, tissue, and cellular levels. In natural plants, mescaline concentrated in active meristems, epidermal tissues, and protruding parts. Artificially spiked Lophophora diffusa products showed no such topographic difference, allowing natural and artificial products to be distinguished. The overlap of mescaline distribution with vascular bundles supported the known synthesis and transport theory of mescaline, suggesting the technique's potential for botanical research.

DOI: 10.3389/fpls.2023.1066595 Mescaline Mass spectrometry imaging Matrix chemical analysis Spatial distribution +7

How to sample a seizure plant: the role of the visualization spatial distribution analysis of Lophophora williamsii as an example.

Forensic sciences research June 1, 2023 Jiaman Lin, Keming Yun, Qiran Sun et al. 2 citations

Mescaline is concentrated in the epidermal tissues and the meristematic tissues of the crown of Lophophora williamsii (peyote), as shown by a validated MALDI mass spectrometry imaging method. Low-temperature storage at -80°C, drying of flower samples, and cutting 40 μm thick sections at -20°C using gelatin as embedding medium are appropriate preparation conditions. Using DCTB as an auxiliary matrix and a laser intensity of 45 are favorable parameters for mescaline analysis. These findings provide a basis for determining the best sampling locations for mescaline in peyote and offer a reference for optimizing storage and preparation conditions for raw plant organs before MALDI detection.

DOI: 10.1093/fsr/owad014 Full text Mescaline Peyote Lophophora williamsii Maldi-msi +3