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W Antopol Dagger

Icahn School of Medicine at Mount Sinai

1 paper in the library · 1 citation · publishing 1977

Papers

Binding of Mescaline with Subcellular Fractions upon Incubation of Brain Cortex Slices with [14C] Mescaline

Pharmacology January 1, 1977 R. K. Datta, W Antopol Dagger, J. J. Ghosh 1 citation

When brain cortex slices were incubated with glucose, about 65% of radioactive mescaline entered the slices. Roughly one-third of this radioactivity became bound to subcellular components including nuclei, mitochondria, microsomes, and ribosomes. Dialysis did not substantially remove the bound radioactivity. The uptake into slices and binding to subcellular fractions increased over time but were reduced by potassium cyanide, absence of glucose, or heating to 80°C for one minute.