Extraction of N, N-dimethyltryptamine (DMT) from Mimosa tenuiflora, syn. Mimosa hostilis (Tepescohuite) using supercritical CO 2 and study of its surface activity
Natural Product Research December 6, 2025 Miguel Gonzalo Arenas-Quevedo, Eduardo Olvera-Santillan, Jesús Gracia‐fadrique
Supercritical CO2 extraction of Mimosa tenuiflora (Tepescohuite) bark yields N,N-dimethyltryptamine (DMT), an indole alkaloid with potential for neuropsychiatric, antiseptic, and wound-healing applications. Extractions were conducted at 314–328 K and 8–22 MPa. The extract's surface tension in water was measured at 308.15 K, and its foaming properties were evaluated at 298.15 K. The work suggests M. tenuiflora is a sustainable source of bioactive and surface-active compounds for pharmaceutical and biotechnological use.