Single Versus Repeated Sessions of Ketamine-Assisted Psychotherapy for People with Heroin Dependence
Journal of Psychoactive Drugs March 1, 2007 Evgeny Krupitsky, Andrei M. Burakov, I. V. Dunaevsky et al. 176 citations
People with heroin dependence who received three sessions of ketamine-assisted psychotherapy (KPT) were more likely to remain abstinent at one-year follow-up than those who received only one session. In a randomized trial, 59 detoxified inpatients first received a KPT session before discharge, then were assigned to either two additional monthly KPT sessions plus counseling or two monthly counseling sessions alone. At one year, 50% (13 of 26) of the multiple-session group stayed abstinent, compared to 22.2% (6 of 27) of the single-session group. No differences emerged between groups in depression, anxiety, craving for heroin, or understanding of life meaning. Three KPT sessions appear more effective than one for promoting abstinence.