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Mark A. Frye

Mayo Clinic

1 paper in the library · 2 citations · publishing 2024

Papers

Selective Serotonin Reuptake Inhibitor Discontinuation for Psilocybin Treatment and Contributions to Alcohol Addiction Relapse

The Journal of Clinical Psychiatry August 25, 2024 Mark A. Frye, Balwinder Singh, Scott Breitinger et al. 2 citations

A man with alcohol use disorder (AUD) maintained sobriety while taking an SSRI and naltrexone, but stopped the SSRI to take part in a psilocybin ceremony, after which he relapsed to alcohol use. The case examines factors that likely contributed to the relapse, including the discontinuation of the SSRI, the context of the psilocybin experience, and the absence of structured follow-up care.