Psychoactive mushroom edibles: trends and toxicities reported to the United States National Poison Data System®, 2023–2024
Clinical Toxicology January 6, 2026 D. Jorgenson, Eliezer Santos León, J. Priyanka Vakkalanka et al. 1 citation
Among 362 reported exposures to psychoactive mushroom edibles, most involved a single substance and were intentional. Polysubstance exposures more than doubled the odds of hospital admission and of moderate or worse toxicity. Confusion and central nervous system depression were also strongly linked to admission and greater severity. No deaths occurred. The effects of these unregulated products are unpredictable, and clinical presentations vary widely.