Detoxification from methadone using low, repeated, and increasing doses of ibogaine: A case report
Journal of Psychedelic Studies April 1, 2017 Clare Wilkins, Rafael G. Dos Santos, Jordi Solà et al. 15 citations
A woman on methadone maintenance treatment for 17 years self-treated with several low and cumulative doses of ibogaine over 6 weeks. Each dose attenuated withdrawal symptoms for hours and reduced tolerance to methadone until all withdrawal signs disappeared. No serious adverse effects occurred, and QTc measures never reached clinically significant scores. Twelve months after treatment, she was no longer on methadone maintenance. This first case report suggests that low and cumulative ibogaine doses may reduce withdrawal symptoms in patients on methadone maintenance treatment, though clinical trials are lacking.