The impact of childhood trauma and cannabis use on paranoia: a structural equation model approach.
Psychological medicine August 8, 2025 Giulia Trotta, Edoardo Spinazzola, Hannah Degen et al. 4 citations
Childhood trauma, especially emotional and physical abuse, is strongly linked to paranoia, and cannabis use amplifies that effect. In a survey of 4,736 adults, those who experienced childhood trauma reported higher paranoia, and weekly cannabis use—measured in standard THC units—also predicted greater paranoia. Cannabis use partially mediated the link between trauma and paranoia, though trauma itself had a much larger direct effect. The findings suggest that assessing both trauma history and cannabis exposure in standard THC units could improve risk detection and guide interventions for people with childhood trauma.