Intracranial Pressure-Guided Therapy in 3,4-Methylenedioxymethamphetamine (MDMA)-Induced Cerebral Edema: A Case Report
Cureus August 1, 2025 Haytham Khalifa, Mohamed Abdulmajeed 2 citations
A 21-year-old woman collapsed after taking MDMA (ecstasy) and drinking large volumes of water, developing severe cerebral edema and hyponatremia. She was intubated, transferred to a tertiary center, and managed with intracranial pressure (ICP) monitoring and careful sodium correction. She made a full recovery and was discharged from intensive care within four days. This case illustrates that ICP-guided management can help optimize care and reduce risks in patients with MDMA-related cerebral edema.