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David F. Nichols

1 paper in the library · 6 citations · publishing 1990

Papers

Structure-Activity Relationships of MDMA and Related Compounds: A New Class of Psychoactive Agents?

Ecstasy: The Clinical, Pharmacological and Neurotoxicological Effects of the Drug MDMA January 1, 1990 David F. Nichols, Robert Oberlender 6 citations

Evidence from drug discrimination studies suggests that MDMA and similar substances form a distinct pharmacological class called entactogens, separate from other known drug classes. Results from multiple laboratories, though still incomplete, support the view that entactogens have a unique pharmacology, as demonstrated by their discriminative stimulus properties, including training dose effects and patterns of complete substitution that differ from those of other compounds.