3 papers in the library · 65 citations · publishing 1990
Ecstasy: The Clinical, Pharmacological and Neurotoxicological Effects of the Drug MDMA January 1, 1990 Alexander T. Shulgin 35 citations
A complete history of a highly controversial topic is impossible because proponents and skeptics state their beliefs with equal confidence. While some historical facts remain uncontested, many are shaped by opinions that influence interpretation. Other facts are kept secret for legal or privacy reasons, and some are simply lost forever.
Ecstasy: The Clinical, Pharmacological and Neurotoxicological Effects of the Drug MDMA January 1, 1990 Graeme P. Dowling 24 citations
MDMA (Ecstasy) and MDEA (Eve) are synthetic amphetamine analogues that gained popularity as recreational drugs among college students and young professionals. Despite widespread use—estimated at 30,000 doses monthly in the US by 1985—emergency room admissions were remarkably low, with only eight reported from 1977 to 1985. Well-documented deaths related to these drugs are exceptionally rare. Uncontrolled clinical trials suggested MDMA might facilitate therapeutic communication and increase patient insight and self-esteem, but the drugs were generally regarded as safe with minor short-term side effects.
Ecstasy: The Clinical, Pharmacological and Neurotoxicological Effects of the Drug MDMA January 1, 1990 David F. Nichols, Robert Oberlender 6 citations
Evidence from drug discrimination studies suggests that MDMA and similar substances form a distinct pharmacological class called entactogens, separate from other known drug classes. Results from multiple laboratories, though still incomplete, support the view that entactogens have a unique pharmacology, as demonstrated by their discriminative stimulus properties, including training dose effects and patterns of complete substitution that differ from those of other compounds.