Human Deaths and Toxic Reactions Attributed to MDMA and MDEA
Ecstasy: The Clinical, Pharmacological and Neurotoxicological Effects of the Drug MDMA January 1, 1990 Graeme P. Dowling 24 citations
MDMA (Ecstasy) and MDEA (Eve) are synthetic amphetamine analogues that gained popularity as recreational drugs among college students and young professionals. Despite widespread use—estimated at 30,000 doses monthly in the US by 1985—emergency room admissions were remarkably low, with only eight reported from 1977 to 1985. Well-documented deaths related to these drugs are exceptionally rare. Uncontrolled clinical trials suggested MDMA might facilitate therapeutic communication and increase patient insight and self-esteem, but the drugs were generally regarded as safe with minor short-term side effects.