Identification of 1-(thiophene-2-carbonyl)-LSD from blotter paper falsely labeled "1D-LSD".
Forensic toxicology January 1, 2024 Yuki Okada, Kazuki Ueno, Noriko Nishiwaki et al. 8 citations
Blotter paper labeled "1D-LSD" was seized and analyzed. Although the label suggested the compound was 1-(1,2-dimethylcyclobutane-1-carbonyl)-LSD, chemical analysis using GC/MS, LC/MS, high-resolution mass spectrometry, and NMR spectroscopy revealed the actual substance to be 1-(thiophene-2-carbonyl)-LSD, a different lysergamide. This is the first reported seizure of this compound and the first LSD analog where an aromatic carboxylic acid was condensed to LSD. The finding highlights that drug-infused blotter paper may contain substances inconsistent with their labeling, and authorities should remain vigilant for newly emerging lysergamides.