Characterisation of a proposed internet synthesis of N,N-dimethyltryptamine using liquid chromatography/electrospray ionisation tandem mass spectrometry.
Journal of chromatography. A August 14, 2009 Cláudia P.B. Martins, Sally Freeman, John F. Alder et al. 11 citations
A purported two-step internet recipe for making the psychoactive compound DMT was tested and found to produce almost none. The second step, methylation of tryptamine, was analyzed with advanced mass spectrometry. Instead of DMT, the reaction yielded 47.4% 1-N-methyl-TMT, 21.0% TMT, 11.1% unreacted tryptamine, and a 0.5% trace of N-methyltryptamine. The work demonstrates that synthetic methods circulated online can be unreliable and produce largely unintended, non-psychoactive products.