Adolescents' trajectories of mental health in the MYRIAD trial.
JCPP advances October 7, 2025 Carolina Guzman Holst, Simona Skripkauskaite, Jack L. Andrews et al.
Most adolescents (69%-80%) followed stable low-problem trajectories for depression risk, social-emotional-behavioural functioning, wellbeing, and anxiety over a one-year school-based mindfulness intervention trial. However, 11%-23% experienced stable high-problem trajectories, 2%-16% showed increasing problems, and 1%-5% showed decreasing problems. Receiving the mindfulness intervention did not affect which trajectory adolescents followed. Individual factors like executive functioning difficulties and baseline mental health risk, along with school climate, predicted trajectory membership, but these effects did not differ between intervention and control groups. The findings indicate that universal interventions may not address the diverse needs of all students.