REVOLUTIONIZING DEPRESSION TREATMENT: A PARADIGM SHIFT OF KETAMINE THERAPY – A SYSTEMATIC REVIEW
Asian Journal of Pharmaceutical and Clinical Research August 7, 2024 Yuvraj Kaushal, Pranav Goyal, Arshiya Sehgal
Ketamine therapy rapidly reduces depression symptoms, with effects appearing within 40 minutes of infusion and lasting up to a week, according to a systematic review of 14 clinical studies. The treatment also helps anxiety and self-assessed depression, with some studies showing long-lasting benefits. Ketamine is generally safe, with most side effects occurring on the day of administration. The review highlights ketamine as a fast and effective biological treatment, particularly for treatment-resistant depression, potentially complementing or replacing existing options. Further research is needed to determine optimal dosing intervals, long-term side effects including cognitive impairment, and relapse rates.