Associations between psychedelic use and adverse outcomes in substance use disorders: a real-world EHR-based cohort study.
Front Psychiatry October 24, 2025 Fares Qeadan, Ashlie McCunn, Benjamin Tingey et al.
Using electronic health records, this cohort study examined associations between psychedelic use and adverse outcomes in people with substance use disorders. The analysis found that psychedelic use was linked to a higher risk of certain adverse events, including emergency department visits and hospitalizations, compared to no psychedelic use. The findings suggest potential risks associated with psychedelic use in this population, though the observational design cannot establish causality.