Nursing
December 1, 2025
Rebecca Ann Ivory, Kathryn M Pate, Brentyn M Jones et al.
Major depressive disorder affects around 332 million people globally, and about 53% of those diagnosed receive pharmacologic treatment, including ketamine. Nurses need to understand ketamine and other emerging therapies for chronic depression and acute suicidal thoughts. This article describes best nursing practices for using ketamine in behavioral health settings, particularly off-label ketamine infusion continuation therapy for treatment-resistant major depressive disorder and acute suicidal ideation and behaviors. It emphasizes whether ketamine is used as an adjuvant or primary treatment.
Nursing
August 1, 2025
Alyssa Jones, Allison Schultz, Makayla Vanderpoorten et al.
A quality improvement project introduced a mindfulness campaign to reduce burnout among ICU nurses, whose stress was worsened by the COVID-19 pandemic. Nurses used the 5-4-3-2-1 sensory engagement method and carried badge cards for quick reference. Pre- and post-intervention surveys using the Maslach Burnout Inventory showed a small effect size across all three subcategories, with a nonsignificant decrease in emotional exhaustion scores. The intervention offered a helpful stress management tool, but the authors suggest that meaningful reduction in burnout requires institution-level changes to address systemic stressors and support nurse retention.
Nursing
July 1, 2025
Meghann L Costa, Maria Wheeler
Psychedelic use in clinical settings is emerging as a treatment for psychiatric illnesses, but most use occurs recreationally without standard protocols, increasing the risk of adverse reactions or 'bad trips.' The article discusses the use and risks of 'trip killers' and 'trip sitters,' and outlines key considerations for nurses caring for patients who use these drugs.
Nursing
November 17, 2023
Lorazepam is associated with worse progression-free survival. A co-treatment approach improves efficacy. The FDA's approval process for certain drugs is questionable. Updates to toxicity diagnosis and management are provided. A method to identify children with acute sinusitis who are likely to benefit from antibiotics is described. Psilocybin is presented as a novel intervention for depression.