A Comprehensive Review of the Current Status of the Cellular Neurobiology of Psychedelics
Biology October 28, 2023 Blerida Banushi, Vince Polito 26 citations
Psychedelic substances may offer therapeutic benefits for psychiatric disorders by acting through specific cellular mechanisms. This review describes how these compounds primarily signal through the 5-HT2A receptor and promote neural plasticity via the TrkB-BDNF pathway. It also covers their effects on other receptors and pathways, as well as their potential anti-inflammatory properties. The work highlights a promising direction for developing new mental health treatments.